Reverse transcriptase-free detection of viral RNA using Hemo Klentaq DNA polymeraseArticle Published on 2022-12-152022-11-15 Journal: Analytical biochemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] affected amplification Analysis can be used caused comparable COVID-19 Degraded RNA demonstrated determine DNA polymerase Efficiency freeze-thaw cycles limitations Nasopharyngeal swab Nearby Nearby primers overcome pandemic patients PCR polymerase chain polymerase chain reaction Primers provide provided reliability reverse transcriptase Reverse transcriptase activity reverse transcription RNA RT-PCR SARS-CoV-2 SARS-CoV-2 detection target transcriptase Viral RNA Viral RNA. [DOI] 10.1016/j.ab.2022.114960 PMC 바로가기
Surveillance of SARS-CoV-2 in nine neighborhood sewersheds in Detroit Tri-County area, United States: Assessing per capita SARS-CoV-2 estimations and COVID-19 incidenceResearch article Published on 2022-12-012022-10-05 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] 5-hydroxyindoleacetic acid acute respiratory syndrome Assessing Biomarker Biomarkers collected Community Comparisons Concentration coronavirus correlation COVID-19 COVID-19 burdens COVID-19 case COVID-19 incidence creatinine cumulative demographic characteristics demographics Detroit Detroit Tri-County area Epidemiology genomic indicate Infection N1 and N2 nine normalized parameter polymerase chain Population predict quantified reduced RNA concentration SARS-CoV-2 SARS-CoV-2 RNA normalization screened selected suggested the disease transcriptase wastewater Wastewater-based epidemiology with COVID-19 xanthine [DOI] 10.1016/j.scitotenv.2022.158350 [Article Type] Research article
HIV suppression was maintained during the COVID-19 pandemic in Malawi: a program-level cohort studyResearch article Published on 2022-10-012022-10-05 Journal: Journal of clinical epidemiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI adjusted adjusted odds ratio age Antiretroviral therapy ART Care clinics cohort study collected COVID-19 COVID-19 epidemic COVID-19 pandemic Critical declined Evidence examined Government HIV introduced logistic regression models Malawi measure multiple imputation National NNRTI no difference objective outcome pandemic Patient patients population-based cohort predictor protease reduce reduced regimen regimens Result routine SARS-CoV-2 Sex Spread stratified Support Suppression of HIV replication transcriptase transfer Treatment Treatment outcome treatment regimen Viral load VL testing with HIV [DOI] 10.1016/j.jclinepi.2022.06.019 [Article Type] Research article
Ethnicity, Comorbid Medical Conditions, and SARS-CoV-2 Test Cycle Thresholds in the Veteran PopulationArticle Published on 2022-10-012022-11-15 Journal: Journal of racial and ethnic health disparities [Category] COVID19(2023년), SARS, 진단, [키워드] access Access to health care addition Admission affected African American age Care center clinical Clinical course Clinical pathology collected COVID-19 COVID-19 infection cycle difference disease severity Ethnic groups Ethnicity Factors Gender Health ICU care increases in information Intensive Medical conditions Molecular pathology outcome Patient Philadelphia polymerase chain Population Population demographics positive public health Quality Quality assurance Quality control required Research retrospective RT-PCR SARS-CoV-2 SARS-CoV-2 RT-PCR test SARS-CoV-2. significantly statistically significant Test tested transcriptase veteran Viral load viral loads was performed [DOI] 10.1007/s40615-021-01114-4 PMC 바로가기
The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19Article Published on 2022-10-012022-11-16 Journal: Annals of internal medicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI acute SARS-CoV-2 infection antibody Antigen baseline Biomarker body mass index Characteristics Clinical outcome clinically COVID-19 cross-sectional study delta variant discharge elevated ENhance enrolled Enrollment evaluate evaluated Factor Government greater higher odd hospital Hospital admission hospital discharge Hospitalized hospitalized patient hospitalized patients identify immunocompromising condition Infectious diseases Inpatient Laboratory less Level Logistic regression Male sex median Multiple multivariable N antigen nasal nasal swab Noninvasive ventilation Odds ratio operation outcome outcomes participant pathogenesis of COVID-19 pathogenesis of SARS-CoV-2 Patient patients with COVID-19 plasma Platform trial point-of-care polymerase chain predict quantification regression models Remdesivir renal impairment SARS-CoV-2 SARS-CoV-2 nucleocapsid severity speed Support Symptoms Therapeutics transcriptase viral replication was determined was measured were assessed worsened worsening [DOI] 10.7326/M22-0924 PMC 바로가기
Laboratory and field evaluation of the STANDARD Q and Panbio™ SARS-CoV-2 antigen rapid test in Namibia using nasopharyngeal samplesArticle Published on 2022-09-272022-11-15 Journal: PLoS ONE [Category] SARS, 변종, 진단, 치료기술, [키워드] Ag-RDT Ag-RDTs alternative Antigen Asymptomatic Coronavirus disease 2019 country COVID-19 COVID-19 infection detect diagnostics evaluated Laboratory nasopharyngeal sample nasopharyngeal swabs new SARS-CoV-2 Participants polymerase Rapid test resource resources RT-PCR SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 testing sensitivity specificity symptomatic transcriptase Transmission variants of concern was reduced [DOI] 10.1371/journal.pone.0269329 PMC 바로가기
Laboratory Interventions to Eliminate Unnecessary Rapid COVID-19 Testing During a Reagent ShortageObservational Study Published on 2022-09-022022-10-04 Journal: American journal of clinical pathology [Category] SARS, 임상, [키워드] acute respiratory syndrome Analysis Computerized physician order entry coronavirus coronavirus disease COVID-19 COVID-19 test COVID-19 tests Dashboard decision Decision support decrease diagnostic evaluate facilitated informatics Intervention Laboratory Laboratory stewardship management pandemic Performing polymerase chain postintervention Rapid Rapid diagnostic test Rapid test reagent resource retrospective SARS-CoV-2 SARS-CoV-2. significantly study period Testing transcriptase [DOI] 10.1093/ajcp/aqac063 PMC 바로가기 [Article Type] Observational Study
Anti-factor H antibody associated hemolytic uremic syndrome following SARS-CoV-2 infectionSARS-CoV-2 감염 후 항인자 H 항체 관련 용혈성 요독 증후군Case Reports Published on 2022-09-012022-09-11 Journal: Pediatric Nephrology (Berlin, Germany) [Category] MERS, SARS, 진단, 치료기술, [키워드] Abnormalities Abstract Alternative complement pathway antibody Atypical autoantibody CFHR1 Chain Reaction complement Complement factor H related protein consecutive patient Coronavirus 19 cut-off Cyclophosphamide dialysis disease episode of estimated glomerular filtration rate Factor Factor H febrile illness filtration rate Follow-up Genetic Genetic studies glomerular filtration rate hemolytic uremic syndrome homozygous Increased information initial management median median titer mycophenolate mycophenolate mofetil New one patient pandemic Pathogenesis Patient patients plasma plasma exchanges polymerase chain polymerase chain reaction Prednisolone ranged required respiratory respiratory symptom respiratory symptoms reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS-CoV-2 SARS-COV-2 infection screened serology Specific thrombotic microangiopathy Thrombotic microangiopathy. transcriptase Trigger triggered uremic syndrome [DOI] 10.1007/s00467-021-05390-4 PMC 바로가기 [Article Type] Case Reports
Perspectives of people living with HIV-1 on implementation of long-acting cabotegravir plus rilpivirine in US healthcare settings: results from the CUSTOMIZE hybrid III implementation-effectiveness studyArticle Published on 2022-09-012022-11-15 Journal: Journal of the International AIDS Society [Category] 치료제, [키워드] acceptability Administered African American All participant antiretroviral Antiretroviral therapy appropriateness baseline black conducted COVID-19 pandemic Data collection eight enrolled evaluated healthcare HIV clinics HIV-1 implementation injection Injections integrase strand transfer inhibitor non-nucleoside reverse transcriptase inhibitor Pain participant Patient Perspective PLHIV Quantitative Randomly receive receiving regimen remained reported RNA Satisfaction selected subset suppressed Tablet therapy time total score transcriptase transfer Treatment treatment satisfaction. [DOI] 10.1002/jia2.26006 PMC 바로가기
Evaluation of a new “all in one” SARS-CoV-2 antigen-detecting rapid diagnostic test and self-test: Diagnostic performance and usability in child and adult populations새로운 "올인원" SARS-CoV-2 항원 검출 신속 진단 테스트 및 자가 테스트 평가: 어린이 및 성인 인구의 진단 성능 및 유용성Multicenter Study Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Adults age Antigen antigen testing Chain Reaction children children COVID testing classic COVID COVID-19 diagnostic diagnostic test diagnostic testing diagnostic tests Epidemics evaluate evaluated faster Health health priorities investigated less majority multicenter multicenter study multiplex nasal Nasal sampling nasal swab nasopharyngeal sample Nasopharyngeal samples Other respiratory viruses participant performed Perspective point-of-care polymerase chain polymerase chain reaction Population Rapid diagnostic test respiratory infections respiratory viruses reverse transcriptase Reverse transcriptase polymerase chain reaction risk RT-PCR Saliva SARS-CoV-2 Self-test specificity switching transcriptase trauma Usability usability. [DOI] 10.1002/jmv.27812 PMC 바로가기 [Article Type] Multicenter Study